IL-22 (C-hIgG2 Fc), Human, Recombinant


IL-22 (C-hIgG2 Fc), Human, Recombinant

货号:PCK185

价格:¥1780¥4980¥18980¥27980

规格:

10µg

  • 10µg
  • 50µg
  • 500µg
  • 1mg

  • 产品概述
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产品概述

产品信息

别名 Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-Derived-inducible factor; IL-TIF; IL22
物种 Human
表达宿主 Human Cells
序列信息 asd
检索号 Q9GZX6
分子量 43.4 kDa
表观分子量 50-62 kDa
标签 C-hIgG2 Fc
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Interleukin-22 (IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 Receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 Receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding Protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by Cytokine IL-17A.
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PC-3 (人前列腺癌细胞) (STR鉴定正确)

  • 产品概述
  • STR鉴定
  • 参考文献
  • 相关产品推荐

产品概述
产品信息
名称 PC-3 (人前列腺癌细胞) (STR鉴定正确)
别称 PC3; PC.3
背景描述 PC-3细胞源于一位62岁白人男性Ⅳ级前列腺腺癌患者的骨头转移灶;PC-3细胞的酸性磷酸酶活性和5-α-睾丸激素还原酶活性都低。
种属
年龄(性别) 男;62岁
组织来源 前列腺;骨腺癌转移灶
生长特性 贴壁细胞
细胞形态 上皮细胞样
细胞类型 肿瘤细胞
肿瘤类型 前列腺癌细胞
生物安全等级 1
生长培养基 Ham’s F-12K+10% FBS+1% P/S
推荐传代比例 1:3-1:4
推荐换液频率 2~3次/周
倍增时间 ~25-50 hours
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养条件 气相:空气,95%;CO2,5% 温度:37℃
致瘤性 Yes, in semi-solid medium. Yes, tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells.
抗原表达情况 HLA A1, A9
基因表达情况 HLA A1, A9
保藏机构 ATCC; CRL-1435 ATCC; CRL-7934 DSMZ; ACC-465 ECACC; 90112714

STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 11
    D2S1338 18,20
    D3S1358 16,16
    D5S818 13
    D7S820 8,11
    D8S1179 13
    D13S317 11
    D16S539 11
    D18S51 14,15
    D19S433 14
    D21S11 29,31.2
    FGA 24
    PentaD 9
    PentaE 10,17
    TH01 6,7
    TPOX 8,9
    vWA 17
    D6S1043 18
    D12S391 21
    D2S441 10,11
  • STR鉴定图

参考文献
文献列表
  • LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway(2021/08/19)

    作者:Xiuyan Wang, Bin Song, Mingcui Zang

    期刊:Journal Of Cellular And Molecular Medicine

    DOI:10.1111/jcmm.16657

    影响因子 :5.295

    引用产品:CL-0004 CL-0046 CL-0075 CL-0143 CL-0185

  • A ratiometric near-infrared fluorescence strategy based on spiropyran in situ switching for tracking dynamic changes of live-cell lysosomal pH(2019/03/27)

    作者:Jin Li, Xiaokang Li, Jianbo Jia

    期刊:Dyes And Pigments

    DOI:10.1016/j.dyepig.2019.03.060

    影响因子 :5.122

    引用产品:CL-0103 CL-0149 CL-0185 CL-0519

  • NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway(2020/3/28)

    作者:Shengjun Luo, Lan Shao, Zhixiong Chen

    期刊:Experimental Cell Research

    DOI:10.1016/j.yexcr.2020.111981

    影响因子 :3.9050

    引用产品:CL-0185

  • 点击展开收起列表

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  • HFSF [HFSF-PI3] (人胚胎眼巩膜成纤维细胞)(暂不出售)

PC-3细胞专用培养基


PC-3细胞专用培养基

货号:CM-0185

价格:¥550¥¥

促销价:¥350

规格:

125mL×4

  • 125mL×4

  • 产品概述
  • 相关产品推荐

产品概述

产品简介

PC-3细胞专用培养基由普诺赛技术团队精心优化,经过长期测试,本产品可保持PC-3细胞最佳的生长状态。本产品中已包含PC-3细胞生长所需的各种成分,无需添加任何成分,可直接用于PC-3细胞的体外培养。本产品仅供进一步科研使用,不得用于诊断、治疗、临床、家庭及其它用途。

产品说明

产品形态 液体
产品浓度
产品规格 125mL×4
培养基成分 Ham’s F-12K(PM150910)+10% FBS(164210-50)+1% P/S(PB180120)
细菌检测 阴性
真菌检测 阴性
支原体检测 阴性
细胞生长实验 细胞生长良好,形态正常
内毒素含量(EU/mL) ≤3
储存条件 2℃-8℃,避光储存
运输条件 冰袋冷藏运输
有效期 3个月

注意事项

1、使用产品时应注意无菌操作,避免污染。
2、本产品含有血清和双抗,如无特别需要不用额外再添加血清和双抗,可以直接使用。
3、为保持本产品的最佳使用效果,不宜将其长时间放置于室温或较高的温度环境中。
4、所有产品请于保质期内使用,超出保质期,必须放弃使用。
5、本产品只供进一步科研使用,不可应用于临床等其他方面。
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