Empty Luer-Lock (with 2 frits) cartridges are designed to be used with SiliaSep cartridges for sample loading.

The use of solid-load technique (also called dry-load) will improve chromatography resolution, especially for compounds soluble only in strong solvents or in large volumes of solvents.

For silica-sample slurry, dry by evaporating the solvent for a more concentrated sample and to eliminate any solvent effect on the purification.

For a dry sample slurry, use a 1:1 ratio (1 g of silica for 1 g of dry sample) but for an oily sample prefer a 3:1 ratio (3 g of silica for 1 g of oily sample).