IL-16/ LCF, Human, Recombinant
货号：PCK175
价格：¥1780¥4980¥20880¥30880
规格：
10µg
- 10µg
- 50µg
- 500µg
- 1mg
- 产品概述
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产品概述
产品信息
| 别名 | Pro-Interleukin-16; Interleukin-16; IL-16; Lymphocyte Chemoattractant Factor; LCF; IL16 |
| 物种 | Human |
| 表达宿主 | E.coli |
| 序列信息 | asd |
| 检索号 | AAC12732.1 |
| 分子量 | 13.4 kDa |
| 表观分子量 | 18 kDa |
| 生物活性 | Measured by its to chemoattract human CD4+ T-lymphocytes using a concentration range of 10.0-100.0 ng/ mlThe ED50 for this effect is typically 0.1 ug/ mL. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Interleukin-16 (IL-16) is a CD8+ T cell-Derived Cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that Receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 Receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
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